TBL: Genetic Testing and Personalized Medicine
نویسندگان
چکیده
منابع مشابه
Implementation and utilization of genetic testing in personalized medicine
Clinical genetic testing began over 30 years ago with the availability of mutation detection for sickle cell disease diagnosis. Since then, the field has dramatically transformed to include gene sequencing, high-throughput targeted genotyping, prenatal mutation detection, preimplantation genetic diagnosis, population-based carrier screening, and now genome-wide analyses using microarrays and ne...
متن کاملThe Cost-Effectiveness of Personalized Genetic Medicine The case of genetic testing in neonatal diabetes
OBJECTIVE—Neonatal diabetes mellitus is a rare form of diabetes diagnosed in infancy. Nearly half of patients with permanent neonatal diabetes have mutations in the genes for the ATP-sensitive potassium channel (KCNJ11 and ABCC8) that allow switching from insulin to sulfonylurea therapy. Although treatment conversion has dramatic benefits, the cost-effectiveness of routine genetic testing is un...
متن کاملPersonalized genetic testing and norovirus susceptibility
BACKGROUND The availability of direct-to-consumer personalized genetic testing has enabled the public to access and interpret their own genetic information. Various genetic traits can be determined including resistance to norovirus through a nonsense mutation (G428A) in the FUT2 gene. Although this trait is believed to confer resistance to the most dominant norovirus genotype (GII.4), the spect...
متن کاملGenetic testing, genetic medicine, and managed care.
As modern human genetics moves from the research setting to the clinical setting, it will encounter the managed care system. Issues of cost, access, and quality of care will affect the availability and nature of genetic testing, genetic counseling, and genetic therapies. This Article will explore such issues as professional education, coverage of genetic services, privacy and confidentiality, a...
متن کاملThe Cost-Effectiveness of Personalized Genetic Medicine
OBJECTIVE Neonatal diabetes mellitus is a rare form of diabetes diagnosed in infancy. Nearly half of patients with permanent neonatal diabetes have mutations in the genes for the ATP-sensitive potassium channel (KCNJ11 and ABCC8) that allow switching from insulin to sulfonylurea therapy. Although treatment conversion has dramatic benefits, the cost-effectiveness of routine genetic testing is un...
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ژورنال
عنوان ژورنال: MedEdPORTAL
سال: 2014
ISSN: 2374-8265
DOI: 10.15766/mep_2374-8265.9824